Telomere Inspector Asia Molecular Genetics Laboratory Center

About us

Telomere Inspector Asia (TIA) Molecular Laboratory is an advance molecular biology laboratory with the co-operation withe iCell Research Institute. TIA provide the special laboratory analysis service for future medical therapy abutment such as personalize medicine, TIA provide the advance analysis for cellular aging Telomere Length Analysis since 2012. TIA also provide the consulting service in the molecular biology setting.

Telomere Inspector Asia Laboratory is consisting of the newest technology equipment and the advance analysis machines on the operation of our experienced medical physicians and scientists.

TIA laboratory analysis service is including

1. Telomere length analysis by Quantitative PCR

1.1 Leukocyte Telomere Length Analysis.

1.2 Telomere Length Analysis of other cell types such as mesenchymal stem cell.

Download

1. Telomere Length Test Handbook.pdf

2. Telomere Test Request Form.pdf

3. Telomere length Test Interpretation Suggestion2.pdf

4. Example of Telomere Test Report5.pdf

2. Specific protein on cell membrane such as CD34, CD105, CD90, CD73 by flow cytometry.
Click>>>Circulating Cell Analysis

2.1 Natural Killer (NK Cell) Count Analysis in Blood (CD3-/CD16+ and/or CD56+)
2.2 Stem Cell Count Analysis in Blood.

Hematopoietic Stem Cell (HSC) Count (CD45+/CD34+)

Mesenchymal Stem Cell (MSC) Count (CD45-/CD34-/CD105+)

Endothelial Progenitor Cell (EPC) Count (CD45+/CD34+/KDR+(VEGF2+))

3. Gene expression such as Oct3/4, Sox2 by RT-PCR

4. Soluble specific protein in blood such as VEGF, interferon gramma etc by array flow cytometry and ELISA.

Telomere are a general risk factor underlying most diseases of aging, in contrast to risk factors that are specific to a disease (as cholesterol or CRP is to heart disease). By monitoring your telomere length, we believe you can gain unique knowledge about disease risk, and your rate of biological aging. This knowledge may also help to inform your lifestyle and, eventually, as research reveals more specific applications, it may help inform therapeutic or prophylactic drug choices and decisions.

By monitoring your telomere length, we believe you can gain unique knowledge about disease risk, and your rate of biological aging.

Telomere are the repeated DNA that forms protective caps at the ends of our chromosomes, telomeres perform a similar role to the plastic tip at the end of a shoelace. Like these plastic tips that keep shoelaces from becoming damaged or frayed, telomeres protect our chromosomes from the critical shortening and damage that may ultimately lead to cellular death and loss of health.

Telomeres shorten over time, and this shortening is considered both a marker of cell aging — a clock of the cell's lifespan — as well as a causal factor in cell aging. Telomere shortening is like a "genetic time clock" — indicating a reduced cellular lifespan. When telomeres reach critically short lengths, the clock "runs out of time," and cells cease to function normally and can die altogether. Download

Yes, to some extent.

Mounting evidence suggests that, on average, people with longer immune cell telomeres have reduced risk of diseases

and less disability in old age compared to people with shorter immune cell telomeres 
(See References http://www.telomehealth.com/clinicians/references/index.php)

are a critical mass of studies that show associations between telomere length and lifestyle factors, such as smoking, exercise, high stress, and nutritional factors. Therefore, it is a reasonable assumption that one can protect their telomeres. In vitro studies show that telomere shortening can be slowed, or even reversed, through the natural enzyme telomerase, which synthesizes telomeric DNA. One study so far has observed an increase in telomerase activity (which protects and lengthens telomeres) by persons enrolled in a health program including eating a healthy diet, getting daily exercise, and using stress reduction techniques such as yoga and/or meditation. This study did not have a control group and further studies are needed. In addition, early evidence indicates that a natural product derived from a Traditional Chinese Medicine can activate telomerase and slow the rate of telomere loss in immune cells and in a recent study in humans, a similar product appears to reduce the percentage of short telomeres in immune cells and have positive effects on several biomarkers of aging.

Based on the cross-sectional studies so far, linking telomere length to psychological states or certain lifestyle factors, it is likely that the following may help maintain or even lengthen our telomeres: Vigorous exercise:

Increasing vigorous exercise to 4 to 5 times a week, such as getting on a bike, going for a brisk walk or jog, joining a gym, or practicing yoga, activities that increase your heart rate or make you sweat. Improving nutrition: Eating a low-fat diet, eating less red and processed meat, like hot dogs and sausages, or taking dietary supplements that activate telomerase. Improving metabolism: If overweight, losing some extra weight or reducing waist circumference. Enhancing wellbeing: Reducing psychological stress and depression, and increasing feelings of personal control and purpose in life. Download Telomere and Diseases.pdf